Ageing now should be considered to be something that can be reversed’ says Prof Shai Efrati, having concerns as a geriatrician.
An Israeli doctor stated that oxygen therapy would be utilized to make physical improvements in human cells that “reverse” aging.
In a journal article released on November 18, Shai Efrati revealed that telomeres, the system found at the final of chromosomes, are lengthened by his research team’s 60 days therapy by more than averagely 20%.
He confirmed that the fight towards aging has met a “holy grail”, but there are many doubtful physicians have stressed that he might have gone too far and could create other issues with health.
“Change of diet and physical workout has been suggested to address aging, however it can only slow the progression”, Efrati reported to The Times of Israel. “We’re trying to say that the biological clock can be sent backward and the quality of blood cells can be improved. Which means aging now should be considered to be something that can be reversed”.
In the near future, a large group of people will be able to register for the therapy that he gave in his trial as subjects: a course of sessions in a pressurized — or hyperbaric — chamber, breathing pure oxygen for some of the time – claimed by the Tel Aviv University associate professor. Of course, medical supplies such as medical masks, disposable gloves as well as protective suits are essential in the process and MAZA is happy to provide such support.
The-near- Rishon Lezion non-profit Sagol Center for Hyperbaric Medicine and Research at the Shamir Medical Center, which he manages, offers its oxygen protocol to businesses that are not in Israel. They now sell it in Florida, at the Aviv Clinic at a retirement village, which offers it as one of the solutions to aging. Efrati is serving as a medical adviser for the clinic.
The claim should be considered cautiously, says some other doctors.
“One study can address aging, a complex process with a handful of factors sounds doubtful”, the leading geriatrician Yoram Maaravi, who is not working with the research, spoke to The Times of Israel.
Telomeres are well-known to be one of many factors that has an impact on aging, not just the only one, he said. The changing of Telomeres can only turn back time. Moreover, he argued that claiming lengthening telomeres will result in aging being address, is still too early in the study of the telomere, since most of the knowledge nowadays include studies of mice, but for human.
Maaravi, a chief physician at the geriatric rehabilitation department of Hadassah Medical Center, and head of home rehabilitation in Jerusalem for the Clalit health fund shared the same idea that telomeres can be made longer by actually using oxygen therapy, it might be a backfire of development since people still don’t know much about them. “One time we see cancer is caused by lengthened telomeres,” he stated. “Cancer cells have an enzyme that can lengthen them, manipulating nature is what we have to think for a second time.”
Efrati reported that with telomeres being lengthened, his therapy also results in a senescent cells reduction, the population of which is believed to correlate to the start of a wide range of diseases.
Maaravi claimed that reducing such cells will have an impact, that it is not clear enough to be the basis for aging addressing confirmation. “reduce aging by removing senescent cells?” he asked. “We don’t know yet.”
Professor Shai Efrati from the Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center.
The study Efrati was published right when he gets a group of 35 people aged 64-plus and took blood samples. Then a 60-day course of treatment was given to them, during which they spent stints in a hyperbaric chamber, breathing pure oxygen for some of the time. Throughout the sessions, n95 face masks are required and examination gloves will be used for any physical contacts.
In his other study released in July, he stated that cognitive sense could be improved by the therapy. In the latest research, telomeres are assessed, which resembles protective caps at chromosomes’ ends. The more age the more they get extended and many studies indicate that the speed of physical aging and onset of age-associated problems can be affected by the length.
Results from nine of his participants from his telomere analysis were excluded five as they did not meet standard evaluations and four because of low-quality blood samples. He excluded 15 participants in the analysis of the senescent cells five as they did not meet standard evaluations and 10 because of their bad quality blood samples.
Among other participants who were tested, there was an increase in telomere length, averaging more than a fifth, and a decrease in senescent cells on the same scale, Efrati informed.
“Researchers around the world are trying to develop pharmacological and environmental interventions that activate telomere elongation,” told Efrati. “Our hyperbaric oxygen therapy protocol was capable of obtaining this, proving that reversing the aging process at the basic cellular-molecular level is something possible.”